The Beginning of Human Life Form Essay -- Artificial Protocells Essays

The Beginning of Human Life Form As science and technology advance, an understanding of the origin of life becomes a feasible possibility. Artificial life research seeks to mimic life and to gain knowledge of the origin of life through reenacting it. This research strives to create the simplest possible â€Å"organism† that fulfills all of the requirements of life. These researchers define life as that which can evolve, self-reproduce, metabolize, adapt to environmental changes, and, ultimately, die. A fundamental concept behind research attempts is emergent properties, those that arise in more complex levels and are not predictable from the properties of lower hierarchical levels. Researchers use two approaches to create protolife: the â€Å"bottom up† approach strives to create life from nonliving components, while the â€Å"top down† approach attempts to simplify living cells to create the simplest possible cell and thus give a glimpse of a possible form of the first living cell. The â€Å"bottom up† approach seems to be the more widely attempted method because it is believed that if nature had to start with simple building blocks, we should do the same. There are two theories about the order in which life emerged; â€Å"one [†¦] assumes the primacy of metabolism and cellular organization [while] the other [†¦] assumes the primacy of reproduction and genetic information† (Lifson). Thus, much relevant research focuses on determining whether the origin of life began with self-replicating, information storing molecules (such as RNA or PNA) or with other molecules such as lipids or proteins (which form, for instance, encapsulating membranes). Whatever the order in which these characteristics evolved, there are three components a protocell m... ... Internet document accessed 11/21/04. http://www.geocities.com/giantfideli/ CellNEWS_Scientists_to_Create_A_New_Form_of_Life.html Lifson, Shneior. â€Å"On the Crucial Stages in the Origin of Animate Matter.† Journal of Molecular Evolution (1997) 44:1-8. Rasmussen, Chen, et al. â€Å"Transitions from Nonliving to Living Matter.† Science. Volume 303. 02/13/04. Rasmussen, Steen, et al. Bridging Nonliving and Living Matter. (2003). Bada, Jeffrey L. and Antonio Lazeano. â€Å"Prebiotic Soup—Revisiting the Miller Experiment.† Science. Vol. 300: 745-56. May 2003. â€Å"Scientists Create a Virus.† CreationTalk.com Forum. Internet document accessed 11/21/04. http://www.creationtalk.com/message-board-forum/viewtopic.php?t= 482&view=next Zimmer, Carl. â€Å"What Came before DNA?† Discover. Vol. 25: 34-41. June 2004.

Essays --

Education is very important for human life. It becomes main necessity for human beings. Almost all aspects of life are influenced by education. A human is introduced to education started from born, and it keeps going on until the death. If a human has a good basic education, it will be easy for the next development. Human will be easily accept and adapt their self with new education which more advanced. They can accept values in social life, school, family, and environment. Moreover, of course they will be smart and be respectful human. Sometimes, education is regarded as a sign whether a human is in high class or not. It influences a lot of areas in human life, for example; in the world of work, in getting money, in communicating with others, and in adapting human in this more modern era and advanced technology. First, education influences the world of work. Human are demanded to have skill in its sector. Usually a company conduct interview before recruiting employee. In recruitment process, there are some questions that related to level of education background. Having good quality in education will help a human to get wanted job and of course with balance income. A human who has high level education will get good job easier than a human who has not good education. Moreover, to get a job is very difficult. It shows that education has important role in the world of work. Secondly, education helps human in getting money. Educated human are more useful and easier in getting money because they have something that can be sold. Just by using the skill, they can get money. Furthermore, they do not need to work powerfully because they work use their brain. It is different with an uneducated human. Uneducated human usually work by using ... ...ality of education because that is very helpful in increasing human’s quality. Therefore, education is very important in the survival of a human because it affects many aspects of life. It can be gotten from formal institute and informal institute. However, many human prefer to choose formal education. Usually it is started from elementary school until university. It has big role in forming good personality, such as; responsibility, honesty, and attitude. Responsibility is important thing that must be belonged to every human. Then, honesty comes from the heart. The price of it is very expensive and it cannot be changed by everything. Next is about attitude, it relates to human’s behavior. Attitude cannot be kept hiding because it comes out spontaneously. Human do not need to be worried if they have good habit in behavior, because a good habit shows a good attitude.

A True Betrayal Of Nature :: essays research papers

In Mary Shelley's Frankenstein, Victor betrays nature by creating the Monster. It is the responsibility of nature, and not man, to create human beings. Victor has done something unnatural, he has created life after death, "I have created a monster." Victor is soon punished for interfering with nature when his own creation turns against its creator. The monster murders William Frankenstein, Victor's brother; Henry Clerval, Victor's best friend; and Elizabeth Lavenza, Victor's bride. The Monster kills all those that are closest in Victor's life in a form of retaliation for Victor's creation of a monster, one without a companion, one rejected by all of civilization. "I determined to seek that justice which I vainly attempted to gain from any other being that wore the human form" (Frankenstein, p.136, line 13). It is the death of Victor's family that signifies his punishment " I have never seen a man so wretched a condition" (Frankenstein, p.20). Victor's repentance comes in two parts: when he decides to destroy his own creation: "I am going to unexplored region, to 'the land of mist and snow;' but I shall kill no albatross, therefore do not be alarmed for my safety" (Frankenstein, p.15, line 25) and when the blame shifts from Victor to the Monster, and the Monster decides to kill himself "Cursed, cursed creator! Why did I live?" (Frankenstein, p.132, line 1). The penance is done by the end of the book and the Monster is removed from civilization. However, that is not to say that Victor is absolved of his betrayal. Victor is in constant sorrow for his creation because it caused the death of so many in his life. In the poem "The Rime of Ancient Mariner," the mariner betrays nature by murdering the Albatross: "I had killed the bird that made the breeze blow" (AM, p.08, line 52). The Albatross represents nature. The representation is meaningless to the mariner until he sees the how things are quickly changed after the death: "Water, water everywhere, nor any drop to drink" (AM, p.10, line 02). Finally, after suffering, and losing his entire crew, the mariner realizes the Albatross as a symbol of nature and he comprehends the evil he has done. The mariner receives a sufficient punishment, "I looked upon the rotting sea, and drew my eyes away; I looked upon the rotting deck, and there the dead men lay" (AM, p.18, line 11). After the killing of the Albatross and the loss of the mariner's crew, his suffering include having his soul in agoney soon afterwards.

Kellogg’s® Special K® Target Market Report Essay

Introduction As we know breakfast is one of our daily meals, it is the first meal of the day. However come to this modern era we eat out the lifestyle to makeup our breakfast itself more enjoyable and healthily. Due to the sufficiency alimentation contain in the breakfast cereal, nowadays most of the people are concentrate on it as taking it for breakfast. In this report, I’m going to segment on breakfast cereal industry base on the combination of geographical, demographic, psychographic and behavioral variables. I would like also select one product from the industry itself and describe how the product is positioned. The product that I have been chosen is Kellogg’s – Special K, which is manufactured by The Kellogg Company itself. 1.0 Segmentation Theory Segmentation as known as a process of distinguish buyers which differ in several ways into groups regarding to their needs, characteristics or behaviour. Market segments exist within feckly market. As a marketer, they have to try to different segmentation variables, alone and in combination to find out the best and most meaningful way to identify and analyze the market structure so it is more easily for marketer to achieve in business market ( Kotler. P et al.2006, 218 ). A seller will create a separate marketing program for each buyer as classifying according to their personal preference. Market segmentation comes before the second step and third step, which is market targeting and market positioning in develop idea of targeting market. There are four main major variables to observe in order to analysis consumer market segments, which is:- ( i ) Geographic segmentation Geographic segmentation will be analysing the different geographical such as region, city size, population density and climate. Firms will decide to progress their market into region as one or a few geographic variables according to the geographical differences. ( ii ) Demographic segmentation Demographic segmentation consists of identifying which variables which include age, gender, family sizes, family life cycle, income, occupation,  education, religion and nationality. Demographic segmentation is the most popular element for segmentation analysis as consumer wants and demands are observe throughout the demographic segmentation ( Kotler. P et al.2006, 230 ). ( iii ) Psychographic segmentation Psychographic segmentation are divided into different groups based on socioeconomic, status, values, attitudes and lifestyle grouping and personality. Basically, psychographic segmentation is used to combine with others segmentation variables as to analysis consumer market segments. ( iv ) Behavioural segmentation Behavioural segmentation that enables buyers to group which are purchase occasion, benefits sought, user status, usage rate, loyalty status, readiness stage and attitude towards product. Behavioural variables also trusted as the best starting point to identify the market segments. As mentioned, segmentation is the element for attempt targeted market and effective marketing plans. Thus, a clear picture and a detailed analysis for the market segments enable a firm to decide the marketing strategic in particular segments. Furthermore, a firm can also benefit from the multidimensional approach to market segmentation and the affiliated benefits are included better matching of customer needs, enhanced profits for business, better opportunities for growth, retain more customers, target marketing communications and lastly, gain share of the market segment. Eventually, a firm definitely will benefit from the multidimensional segmentation as they adopted it. 2.0 Target Market Identification Kellogg’s ® Special K ® is a lightly toasted, lightly sweetened rice cereal, high in flavor sort of breakfast cereal. Basically, it contains 7 fundamental vitamins and minerals which are essential nutrients that be supposed to contains in our breakfast. 2.1 Geographical traits Target market for the product Kellogg’s ® Special K ® are basically stressing on the urban city zone. Busyness lifestyle that implement by the residents result in none alimentation breakfast taken as their very first meal of the day. Targeting on this particular issue, Kellogg’s ® Special K ® are especially made-up for the urban residents. As we known, breakfast cereal can be taken rapidly and Kellogg’s ® Special K ® absolutely satisfy the time lacking issue in pragmatic lifestyle. Furthermore, sufficiently vitamins and minerals contained in Kellogg’s ® Special K ® intent to replenish to the residents who lack of nutrients to go with daily activity. Currently, Kellogg’s ® Special K ® is not only purchasable in nationally but also internationally and it considered as an internationalization’s breakfast cereal. 2.2 Demographic traits Basically, Kellogg’s ® Special K ® is designed for women who want to take the first step at breakfast to help manage their shape, yet there’s no gender, age, life cycle, occupation, education, religion and nationality barrier. Kellogg’s ® Special K ® can be consume by everyone who is concern overall condition in health, and this product especially recommended to the senior citizens and the busyness urban residents as it helps on boosting their metabolism. Nevertheless, the Kellogg’s ® Special K ® product can only purchase by those who have higher income as it is sort of the luxury breakfast cereal and it definitely suitable for urban residents as most of them receive a high wages. 2.3 Psychographic traits Kellogg’s ® Special K ® consider as a luxury product as it cost $16.40 for each and it is much suitable to consume by buyers who have a higher wages. Urban residents are wealthily and Kellogg’s ® Special K ® fits them well as the consumption for their breakfast. Therefore, regarding to the study of VALS lifestyles, it involves study that measuring consumers’ main AIO dimensions, which is activities, interests and opinions. Kellogg’s ® Special K ® is the higher level status product and it is most probably consume by those who are the higher and medium class in socioeconomics,  which have luxury income and affordable for Kellogg’s ® Special K ®. Kellogg’s ® Special K ® consumers are human being who concern to live out an outstanding, healthy and enjoyable lifestyle. They consume Kellogg’s ® Special K ® as result in they attach importance to the essential vitamins and minerals, which are important as part of a ba lanced meal. 2.4 Behavioural traits People who consume Kellogg’s ® Special K ® is much concern to health if compare to the others. Fundamental and various kind of vitamins and minerals become the major element of the consumption of Kellogg’s ® Special K ®. In this compressive stressed century, people are too busy until there is insufficient time for them to take a breakfast. Yet, they need a product which sufficiency provided them the nutrients to start up their daily activity, and this is the purpose Kellogg’s ® Special K ® made for. Most of the consumers reckon that Kellogg’s ® Special K ® gives the essentials of a breakfast and they trust in taking Kellogg’s ® Special K ® is way better instead of eating the breakfast which prepared by themselves. Indirectly, it forms a bound between the consumers and product, which is loyalty to the product. They trust, purchase and consume on Kellogg’s ® Special K ® as Kellogg’s ® Special K ® can lead them to an ideal lifestyle. 3.0 Visually Representing the Target Market Kellogg’s ® Special K ® Geographical traits As we can notice from the packaging of Kellogg’s ® Special K ®, every single word on that particular packaging has been returned in English language printed on it as English is the common language in Australia. Besides that, English also cognizance as the international language in this century. Eventually it shows that the target market for the product Kellogg’s ® Special K ® is differentiated into a lot of geographic variables all over the worldwide. Demographic traits As mentioned, Kellogg’s ® Special K ® is sufficiency alimentation contained and it’s an excellent source of 7 vitamins and minerals. Thus, the target market for the product Kellogg’s ® Special K ® itself is people who require abundance daily nutrients regardless to gender, age, life cycle, occupation, education, religion and nationality barrier. Kellogg’s ® Special K ® contains just 17% sugar, meaning that one 30g serving contains just 5g per bowl, around 1 teaspoon – this is much lower than that contained in other breakfast foods and half that contained in toast with jam (Special K Original. 2009)! It is also 99% of fat free and especially recommended to the women, who keen to kick start to healthy weight management. A great deal in protein will also give them a boost to their metabolism. A malty taste plays a important role to allure their appetite as consuming an enjoyable breakfast. A perfect health weight management Psychographic traits Nowadays, woman and ladies intend to manage their body shape and live out a healthier lifestyle. As we can see from the packaging, a 99% of fat free definitely will attract the consumption by woman, as it is a simple and convenient weight management program. The K letter itself shows in artistic form to inspire the picture of a prefect body shape to the consumer. Besides that, a well looking packaging of Kellogg’s ® Special K ® designed to deserve the purchase cost. It is also shows the ‘snob effect’ as consume it because it is one of the luxury breakfast cereal. All of these have been shown in the pictures of the part of psychographic traits. Behavioural traits Most of the consumers have the some thought towards Kellogg’s ® Special K ® product, which is lead them to a healthier and better standard of health’s condition. The image of cereal which contains 7 fundamental vitamins and minerals will provide sufficient nutrients to the consumers to kick start their brand new day. It helps to form a healthy body by providing the essential nutritions as what written in the nutrition information panel. Reference list Kotler, P. Adam, S. Brown, L. and Armstrong, G. 2006. Pearson Education Australia. Principles of Marketing: Analyzing consumer market segments. Kotler, P. Adam, S. Brown, L. and Armstrong, G. 2006. Pearson Education Australia. Principles of Marketing: Market targeting. Market segmentation – Why segment markets? http://tutor2u.net/business/marketing/segmentation_why.asp (Accessed September 1, 2009) Special K Original http://www.kelloggs.co.uk/whatson/specialk/forum/nutrition/our-products/special- k-original/9230/view-topic.aspx (Accessed September 1, 2009)

Andy Warhol and His work on the Contemporary Art Essay

Andy Warhol (1928-1987) of Pittsburgh, Pennsylvania, less commonly known as Andrew Warhola, was a central figure in the pop art category. He is an American artist who reigned around the world as a painter, author, avant-garde filmmaker and as a public personage for his connection to many people of different fields of work and status. Warhol studied in Carnegie Institute of Technology (now known as the Carnegie Mellon University) to hone his artistry (www. artgallery. com, 2008). Warhol unify his works through the Keatonesque style which is aritistically and personally affectless. In his work s a Pop artist, conceptual aspects were always there as a key factor. His art was known for its irony, in most of its sense. Campbell’s soup cans was probably his most famous work. The mundane images he made were turned to the so-called ironic art through enlargement, hand-painting or silk-screening. He always mentioned that the idea of his work is always at the surface of his work, obvious, apparent. Other attributes of his work were slight color changes using ink spots (www. pbs. org, 2007). His work reveals contemporary art in such a way it concerns some human desires that never ceases to revolve around. He even made his film where he was an international celebrity and a pop artist. His experiences with many people brought him the ideas of what is contemporary, and made sure that no traces of the artists can be recognized from his artwork.

Carefully Read the Poem Simon Lee by William Wordsworth

Simon Lee the Old Huntsman is a poem which occurs in Lyrical Ballads and was written in 1798, belonging, thus, temporally to the Romantic period (1780-1830). Romantic writing is commonly identified with some key elements, which concern imagination, nature, symbolism and myth (although there have been writers of this period who were not as ‘mainstream’). William Wordsworth has been characterised as a canonical author of Romantic Poetry in that his work is highly attached to the notion of Nature and plenty of reference is made to it. Approaching a piece of literary work, however, from this perspective is very restraining, therefore, in this essay we will attempt a ‘social’ or ‘historical’ kind of approach. We shall try to ‘read’ the idealistic language found in the poem as social or historical discourse through the poetic techniques employed by the writer. In other words, we will analyse the way various elements of poetic form and language combine to create meaning and effects. Simon Lee is about an old huntsman who, while was once strong and active, now strives to fight his declined health and strength. The poem recounts an actual encounter of the poet with this old man. It seems to be a hybrid of lyric and narrative (a lyrical ballad). Lyric in that we have a first-person expression of emotion and concentration upon the actions and feelings of an individual at a particular moment, while narrative, since there is a narrator and another character, whom the former encounters and, later, describes. There are 12 stanzas of eight lines each with a rhyme scheme of ABABCDED that causes the lines to flow smoothly. The first stanza of the poem introduces us with Simon and sets the scene: ‘In the sweet shire of Cardigan’. It is obvious from the beginning that Wordsworth is dealing with a matter from common life, since every reader is familiar with and can picture a sweet shire, the same way the notion of ‘pleasant’ is easy to grasp. Furthermore, a series of modest, plain adjectives that evoke sadness are used to describe Simon: ‘old man’, ‘a little man’, who ‘once was tall’ making it clear that the ‘hero’ of the poem is just a humble, ordinary old man. Nature, Wordsworth argued, can save people from the alienation, frustration and triviality of contemporary urban life. It seems to me that by choosing to start the poem placing the readers in a rural area away from urban life, he seeks to evoke feelings opposed to the ones mentioned above, those that are for him connected with away-from-nature settings. The second stanza is, I consider, somewhat tragic, since two totally contradictory adjectives- ‘poor’ and ‘merry’- are used to describe this same person only in two different periods of his life: in the past and present. In this way, the winding down of Simon’s life over the years becomes even more intense to the reader. The rhyming couple ‘has he/ see’ in Lines 1 and 3 of the second stanza is known as poetic inversion. Wordsworth has inverted the word order for the sake of the sound sense of the verse as well as of the rhythm, both of which would have been different if he had used ‘he has’. Perhaps any other choice would have made the rhyme pattern less unfussy than it is now, and complication is what he has tried to avoid throughout the whole poem. The easy rhymes ‘merry/cherry’, ‘sound/round’, ‘sick/thick’, ‘door/poor’ are also justified by this theory. The metaphor ‘like a cherry’ is directly derived from the ‘diction’ of Nature and can be easily comprehended and pictured by the majority of the common population-especially in rural areas. In the fourth stanza the retrospection stops and Simon is no longer in the prime of his life. He is no longer healthy, rather he is ‘poor old Simon Lee’ again, who ‘has no son’, ‘has no child’, he only has ‘an aged woman’ and they both live ‘upon the village common’. Simon Lee is again transformed into the old man that was presented to us in the first stanza and the poetic inversion of ‘village common’ functions to leave an echo of the commonness of everything that surrounds this man, for once more. For the following four stanzas this picture of his is highlighted through words such as ‘lean’, ‘sick’, ‘thin’, ‘dry’, ‘weak’, ‘the weakest in the village’ or the image of his ankles, which are ‘swoln and thick’. By these means, the reader is ‘forced’ to sympathise with the hero, who is totally helpless. Even more, the repetition (which could also be characterised as alliteration) of the phrase ‘he has no’ in Line 5 of the fourth stanza reinforces the sense of loneliness and misery that is created. The same effect is also achieved by the alliteration that occurs between the words ‘sole’ -‘survivor’ in Line 8 of the third stanza. What is strikingly noticeable is that there is a pause at the end of almost each line, either a comma, a semi-colon, a full-stop or an exclamation mark, with occasional exceptions in some lines in an inconsistent pattern. This stylistic device, known as ‘enjambment’, suggests that these exceptional lines actually run on; however, on account of the actual line ending itself (with no punctuation mark) the reader is made to pause for a while and think. In other words, he can read each line slowly. This works to relieve any sense of suspense or tension within the poem. Or we can say that the writer initially aims at reproducing classical qualities of balance, harmony and proportion, while the variations noticed may function to indicate the disturbance that has occurred to the above. Suddenly, in the ninth octave Wordsworth writes directly to the reader –‘My gentle reader’- and asks him to expect no action; the poem is not climactic and the poet is addressing this fact (‘It is no tale’). Through the phrase ‘I perceive’ he reveals his insight into the reader’s reactions (‘ I’ m afraid that you expect some tale will be related’) and he establishes that there is no resolution or climax to be expected. He is also implying the reader’s blindness of the ‘tale’ already told by Simon’s aging body: the fact that he is humbled while he realises that struggling against a decaying organism is hopeless. At this point it might be useful to think of the readers whom this poem was originally created to address. On the one hand, Wordsworth has chosen to include the common people of rural life in his range of audience, and therefore is using their own language. In the ‘Preface’ to his Lyrical Ballads of 1802 he argues that the language of poetry ought to be ‘language of men’. As he says, this is because the rural poor ‘convey their feelings and notions in simple and unelaborated expressions’ (Wu, Romanticism,1994 p. 252). Their habits do not change as they are not affected by fashion, so their language is more sincere. On the other hand, by the phrase ‘my gentle reader’, we could also say that he is addressing the readers belonging to the upper-class of society; the educated people who would expect a more elaborated language and this poem to actually be far less profound that it really is. To those people who cannot see that it functions to be symbolic, but who only see the words and the events without the meaning lying below these. Wordsworth had lived through the Revolutionary period and was against the early ideas, which is why he had the reputation of a radical. He was influenced by the democratic ideas of the period. It seems that through this poem he seeks to change the social circumstances of the time. He seeks for a more democratic state and he attempts to pass this notion through the use of simple, unelaborated language, which is considered as ‘uncorrupted’. Let’s not forget that it was written in a period of remarkable social and political change. Therefore, in one sense, he conducted his own ‘social revolution’, influenced by the social context within which he created poetry. He was against the received idea of poetic language being as refined and eloquent as to be available only to those with an education. We might, thus, say that by addressing his reader in these two stanzas he is being ironic towards this class of society. At the conclusion of the poem, where the only action so far has been the decay of life, this ‘single blow’ in the twelfth stanza seems to be releasing a sense of freedom from this natural law and the writer’s tone suggests this victory over aging and decay. Simon’s response to this comes with ‘The tears into his eyes’ and ‘thanks and praises’ , conveying a shift from negative to positive; from pity to admiration, since attention now passes from Simon’s outward decay to the endless ‘activity’ and openness of his heart. The writer is overwhelmed by this gratitude expressed towards him and suggests that kindness within one’s heart may overcome any physical decay that comes with aging and bring about this spiritual survival that equals physical vigour of youthful.

Look at Macbeth’s Monologue in Act III Scene I, what do we learn about Macbeth? Essay

In Macbeth’s monologue in Act III Scene I, we learn a lot about Macbeth’s insecurities. He tells us that he does not feel safe on the throne because of the witches’ prediction that Banquo’s children will be kings. He fears Banquo because Banquo is brave, and he represents good and he would not approve of how Macbeth obtained the crown, we can see Banquo’s suspicions earlier in this scene when he fears that Macbeth has â€Å"played’st most foully† for the crown. He says that Banquo is clever and as long as Banquo is around, Macbeth will live in fear of him. Macbeth then talks about how the witches have predicted that Macbeth will have no children and his crown is â€Å"fruitless†, and he has a â€Å"barren sceptre† meaning that he will not pass on his crown to anyone in his family. He then says that he only murdered Duncan for Banquo’s children, as they will be the next kings, and it was only for them he gave his soul to the devil and only for them he has become a more evil and treacherous man. He then asks for fate to be kind. This is a clear change in Macbeth’s character here, earlier in the play he was described as â€Å"disdaining fortune† in battle, which means that he did not worry about fate or fortune, he just fought bravely against the odds, but now we see that Macbeth has come to rely on fortune and beg for it to be kind to him. In this monologue Macbeth reveals that he is probably going to kill Banquo and Fleance, Banquo’s son. Earlier in the scene he asked how Banquo was going to get to the banquet at Macbeth’s palace and if Fleance would be going with him. He wants to kill Banquo to stop himself going mad with fear of the witches’ prediction about Banquo â€Å"having kings†. He realises that this may mean that one of Banquo’s children may kill him to become king. He wants to kill Banquo and Fleance, as that will stop Banquo’s line of descendants as Fleance is Banquo’s only son and then Macbeth will be safe in the crown. We can also see that Macbeth is a very insecure person and is especially insecure as a king. He will go to any lengths to make sure that he remains king, even murdering his best friend and his best friend’s son. There are some hints I this passage that Macbeth is going slightly mad. He says that he ahs â€Å"filed his mind†, which means that has corrupted his mind or has gone a bit crazy, by killing Duncan. In this monologue we see some of Macbeth darkest and deepest thoughts. He has changed from the brave, loyal and honourable man that we first were introduced to him as by the dying captain to a man that is willing to murder innocent men for power, and a man that is haunted by predictions made by some old women.